Capitalism is the Great Filter.
Basically, the Fermi Paradox uses reasoning to conclude that the universe should be teeming with life, maybe millions of alien civilizations, but it is not. An interesting and potentially ominous solution to the Fermi Paradox is that civilizations run into a "Great Filter", or insurmountable challenge (or common mistake) that leads to their destruction, before they can take over the universe. We could be past it, as life could be more precious than we know, or it could lie in front of us.
Now, before you throw off the idea that capitalism is the Great Filter, ask yourself if the ones with money and power are attempting to change life as we know it (for the better) or make a profit.