Something becomes culturally significant only when it is no longer culturally relevant. amirite?

Kinda like people thinking the Internet would just be a fad and would die out in a decade or so. Cultural significance can only be recognized in hindsight, because it's the only way we can tell how large of a mark it left.

Men in fights don't hit each others balls, because the will feel it themselves... amirite?

Speak for yourself. If someone bigger or stronger comes at me, I'm going for the eyes and balls.

The universe is still in its infancy and we are probably just one of the first organisms to develop in it, amirite?

Well, yeah, that is one of the potential explanations for the so called Fermi Paradox.

Overindulgence in nostalgia can lead to depression, amirite?
Somewhere there is an industrial nacho cheese production facility with giant vats of liquid cheese to support taco bell and movie theaters. amirite?
@Shiny244 That's just not how manufacturing of FMCG works. Giant vats or silos are typically for ingredients, storage of...

Can confirm. I'm a contractor who has gone to a chili/nacho cheese production facility. It's soooo cool to see the behind the scenes aspect and watch all the nacho cheese get plopped into a bag and machine sealed, then flopped onto a conveyer and into a box for shipping.

Only the poorest rich people fly in first class, amirite?
Women will sit on (about) twice as many toilets in their lives then men will. amirite?

I don't know why men don't want to sit it's very comfortable.

People laugh about how cats love boxes, but if there was suddenly a box bigger than you in your living room, you'd probably go in it too. amirite?
You don't know how your body functions but your brain does, even though you are your brain. amirite?
For all the millions of years of evolution to the human species, dogs and cats have a way better bum-hole for pooping without need for wiping. amirite?
With few exceptions, you don't need to learn algebra or cursive in high school, amirite?

Cursive, sure, like who cares.

But if your high school isn't teaching you algebra they have completely failed you.

Chickens are one of the coolest looking birds, amirite?
When you have a girlfriend and a cat, you need short nails for one pussy and long nails for the other. amirite?

im confused why do you need long nails for the cat?

There is always a minute chance that your laundry will be perfectly folded after a tumble dry. amirite?

I understand the idea here that randomness will has the capability to produce order, but the application is off. Imagine that it just started raining and you are watching the raindrops hit the concrete pavement. There is a nonzero chance that raindrops spell out your first name after a given amount of time. However, toss a crumpled up shirt out into the rain and you can guarantee the precipitation will not fold the shirt. Just like I can guarantee the dryer won't fold it perfectly. It's the wrong kind of randomness for the end result.

Kinda weird that there isn't just free drinking water everywhere. amirite?

I think you should talk to Disney world.